A ferritin test measures the amount of a blood protein called ferritin, which stores iron. Ferritin blood test results may come back as normal, low, or high. You may feel a burning sensation on your tongue. The amount of blood that the doctor removes, and how frequently they remove it, will vary depending on a person’s age, health, and ferritin levels. © 1998-2020 Mayo Foundation for Medical Education and Research (MFMER). It is important that people confirm normal levels with their doctor or the laboratory that tested them. Ferritin that is not combined with iron is called apoferritin. For women, serum ferritin normally ranges from 12 to 150 ng/dL while men range from 12ng/dL to 300ng/dL, or nanograms per deciliter. This article contains the best tips on relieving symptoms. A ferritin test should only take a few minutes. At first, the person may require the removal of around 500 ml of blood weekly until their ferritin levels return to normal. Furthermore, ferritin has significant non-storage roles within the body, such as protection from oxidative damage. Ferritin levels are also commonly elevated when there is underlying inflammation in the body. The protein is produced by almost all living organisms, including archaea, bacteria, algae, higher plants, and animals. High or low levels of ferritin are suggestive of an iron storage disorder or iron deficiency anemia, respectively. The ferritin levels measured usually have a direct correlation with the total amount of iron stored in the body. A ferritin test helps your doctor understand how much iron your body stores. Baby Teething? Within the realm of biological processes it participates in oxidation-reduction, iron ion transport across membranes and cellular iron ion homeostasis. It is responsible for storing iron in the cells. A doctor may order a ferritin blood test, sometimes alongside other tests, to check a person’s iron levels. Medically reviewed by John A. Daller, MD; American Board of Surgery with subspecialty certification in surgical critical care. For the best results, people should take oral iron supplements with a source of vitamin C to increase iron absorption. Clinical manifestations and diagnosis of adult Still's disease. Bacon BR, et al. However, ferritin levels may be artificially high in cases of anemia of chronic disease where ferritin is elevated in its capacity as an inflammatory acute phase protein and not as a marker for iron overload. Learn about the causes, symptoms, and treatments…. Plasma ferritin is also an indirect marker of the total amount of iron stored in the body; hence, serum ferritin is used as a diagnostic test for iron-deficiency anemia.[4]. Ferritin is a universal intracellular protein that stores iron and releases it in a controlled fashion. Ferritin is the major iron storage protein in the body, so the ferritin test is ordered as an indirect way to measure the iron stores in the body. The normal range for ferritin levels is rather broad and varies slightly among laboratories. Your doctor may adjust your diet or supplements. They will sometimes use some cotton wool or a bandage to stop any bleeding, before labeling the blood sample and sending it to a laboratory to be analyzed. You may also have strange cravings for licorice, chalk, dirt, or clay. Serum ferritin levels of 20-60 µg/L in an anaemic pre-pubescent child may represent iron deficiency if there is coexisting inflammatory disease. Ferritin is a protein in the body, especially found in the bone marrow, spleen, skeletal muscles and liver. As ferritin is also an acute-phase reactant, it is often elevated in the course of disease. Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Coronavirus in Context: Interviews With Experts. They should avoid antacids, calcium supplements, and tea or coffee within 2 hours of an iron supplement. In humans, it acts as a buffer against iron deficiency and iron overload. [7] One major trigger for the production of many ferritins is the mere presence of iron;[7] an exception is the yolk ferritin of Lymnaea sp., which lacks an iron-responsive unit. It might happen because of heavy menstruation, pregnancy, anemia, some bleeding in the body (hemorrhoids, ulcers, digestive tract bleeding, etc.
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